Continuous Flow Carbonylation Reactions Eliminating the Use of Toxic Carbon Monoxide

Andrew M. Sales and Application
Specialist at Vapourtec Ltd

Researchers from Janssen Research and Development (Spain), the University of Leuven and the Universidad de Castilla-La Macncha have shown a continuous flow process for carbonylation reactions without the need of toxic carbon monoxide and have shown new chemical reactivity under flow conditions that were not previously possible under batch conditions.

Continuous flow chemistry has developed to be a useful enabling technology that allows access to novel process windows giving excellent control of reaction parameters. The use of this technique contributes to sustainability as it allows hazardous compounds to be better contained and in some cases allows the reduction of these dangerous chemicals while allowing the reaction to be easily scaled.

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Continuous Flow Carbonylation Reactions Eliminating the Use of Toxic Carbon Monoxide Gas Using the Vapourtec R-Series flow chemistry system researchers from Janssen Research and Development (Spain), the University of Leuven and the...

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